Infection with chikungunya virus confers heterotypic cross-neutralizing antibodies and memory b-cells against other arthritogenic alphaviruses predominantly through the b domain of the e2 glycoprotein

HIGHLIGHTS

• who: John M. Powers et al. from the Editor: Alain Kohl, University of Glasgow, UNITED have published the article: Infection with chikungunya virus confers heterotypic cross-neutralizing antibodies and memory B-cells against other arthritogenic alphaviruses predominantly through the B domain of the E2 glycoprotein, in the Journal: (JOURNAL)
• what: Neutralizing antibodies are the primary immune correlate of protection elicited by infection and the major goal of vaccinations in development. The work presented in this manuscript was supported by grants from the National Institutes of Health 1U19AI142790 (DNS) R01AI153434 (WBM) R21AI135537(WBM) UL1TR002369 (WBM) Takeda . . .
  

   

  

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