HIGHLIGHTS
SUMMARY
Quantitative genetics explains and describes inheritance of complex traits such as many diseases in humans and animals or agriculturally relevant targets, e_g, yield and product quality in maize or dairy cattle. It focuses on statistical quantities, e_g, allelic and haplotype frequencies, locus effect sizes, means, variances and covariances between individuals or traits. Interaction is key in biological processes, both at the biochemical (e_g, cycles) and population levels, e_g, the shifting balance theory of evolution. Selection schemes distort inference when estimating differences between treatments or genetic associations between traits, or degrade prediction of outcomes, e_g . . .
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