Inferior olive hcn1 channels coordinate synaptic integration and complex spike timing

HIGHLIGHTS

• who: Derek L.F. Garden from the University of Edinburgh, Edinburgh , XD, UK have published the article: Inferior Olive HCN1 Channels Coordinate Synaptic Integration and Complex Spike Timing, in the Journal: (JOURNAL) of February/13,/2018
• what: The authors demonstrate that vitro network actions of HCN1 channels enable bidirectional glutamatergic responses while local actions of HCN1 channels determine the and waveform of synaptically driven action potentials. The authors focused on Purkinje cells in the vermis of lobule V of the cerebellum, as this region integrates sensory input with motor commands and is involved in adaptive . . .
  

   

  

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