HIGHLIGHTS
- who: A. Marijke Keestra-Gounder and Prescilla Emy Nagao from the Asahikawa Medical University, Japan have published the article: Inflammasome activation by Gram-positive bacteria: Mechanisms of activation and regulation, in the Journal: (JOURNAL)
- future: Future studies will have to determine the underlying mechanisms of NLRP6 activation and immune signaling during infections. procaspase-1 to the complex allowing for autocleavage of caspase-1 processing of pro-IL-1b pro-IL18 and gasdermin D resulting in cytokine secretion and pyroptosis.
SUMMARY
Advances in cell microbiology in relation to invasive bacterial infections, signaling . . .
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