Inflammation: roles in skeletal muscle atrophy

HIGHLIGHTS

  • who: Yanan Ji and colleagues from the University, Nantong, China have published the Article: Inflammation: Roles in Skeletal Muscle Atrophy, in the Journal: Antioxidants 2022, 11, 1686. of /2022/
  • what: This study proposes that inflammation and oxidative stress are major triggers for skeletal muscle atrophy.

SUMMARY

    If protein degradation is faster than protein synthesis, skeletal muscle atrophy occurs, resulting in decreased muscle mass and impaired muscle function, which seriously affects the patient's daily mobility and living ability. Over-activated inflammation further initiates the downstream muscle atrophy program with increased proteolysis . . .

     

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