Inflammatory activation of the fcγr and ifnγr pathways co-influences the differentiation and activity of osteoclasts

HIGHLIGHTS

• who: Bettina Groetsch from the University of Science and Technology of China, China have published the research: Inflammatory activation of the Fcu03b3R and IFNu03b3R pathways co-influences the differentiation and activity of osteoclasts, in the Journal: (JOURNAL)
• what: The authors show that the direct inhibitory effect of IFNg on osteoclast differentiation is dependent on the osteoclast differentiation stage.
• how: The acquired raw data were analyzed using the linear models for microarray data (LIMMA) package of R Bioconductor after uploading the median signal intensities. Osteoclast is dependent on their maturation phase Based on FcgR3 . . .
  

   

  

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