Inflammatory alterations of the extracellular matrix in the tumor microenvironment

HIGHLIGHTS

  • who: Junko Iijima from the Department of Molecular Biosciences, Faculty of Life Sciences, Kyoto Sangyo University have published the paper: Inflammatory Alterations of the Extracellular Matrix in the Tumor Microenvironment, in the Journal: Cancers 2011, 3, 3189-3205 of 28/07/2011

SUMMARY

    Inflammatory cells produce inflammatory mediators, including cytokines, chemokines, and tissue remodeling enzymes, which in turn amplify and perpetuate the inflammatory cascade. Tenascin-C, biglycan, versican, and hyaluronan initiate toll-like receptor (TLR)-mediated innate immune_responses. The hallmarks of chronic inflammation include increased infiltration of activated inflammatory cells, mediator release, and . . .

     

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