Inflammatory gut as a pathologic and therapeutic target in parkinson’s disease

HIGHLIGHTS

  • who: Jea-Young Lee from the Animal preparation and transplantation All experimental procedures were approved by the University of South Florida Institutional Animal Care and Use Committee (IACUC) and followed the ARRIVE , guidelines [47]. All investigators were blind to the treatment condition until after completion of all data analyses. This study used , months-old male C BL/ NJ (wild type or Wt) and C BL/, Tg (Thy SNCA) Mjff/J mice (transgenic or Tg) (The Jackson Laboratory, Bar Harbor, Me). The Tg mice overexpressed the wild type human u03b1-synuclein, with validated phenotypic PD-like progressive nigrostriatal . . .

     

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