Influence of cyp2d6, cyp2c19 and cyp3a5 polymorphisms on plasma levels of tamoxifen metabolites in algerian women with er

HIGHLIGHTS

  • who: Amira Boucenna from the A total of , Algerian females with ­ER Breast Cancer (mean age, ±, ) were included in the present study between February , and December All of these patients underwent mastectomy and lumpectomy at the University Hospital Center of Constantine department of Oncology and Radiotherapy and were treated with Tamoxifen (, mg per day), were recruited between February , and December, . Tamoxifen was considered for an average of , months (range:, months), with a median follow-up of , months. Our study has been approved by the local Ethics Committee. The use of human blood samples and protocols in this . . .

     

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