Influenza a virus strain pr/8/34, but neither ham/2009 nor wsn/33, is transiently inhibited by the pb2-targeting drug paliperidone

HIGHLIGHTS

  • who: Georgios-Dimitrios Panagiotidis from the Institute for Virology, FB10u2011Veterinary Medicine, JustusLiebig University, Giessen, Germany have published the research work: Influenza A virus strain PR/8/34, but neither HAM/2009 nor WSN/33, is transiently inhibited by the PB2-targeting drug paliperidone, in the Journal: (JOURNAL) of 13/01/2023
  • how: Similar results were obtained using the human alveolar basal epithelial_cell line A549 which is also often used in FLUAV research (Supplementary Fig S2).

SUMMARY

    The paliperidone molecule was predicted by modeling to interact with an evolutionarily conserved region of . . .

     

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