Influenza a virus use of bincard1 to facilitate the binding of viral np to importin α7 is counteracted by tbk1-p62 axis-mediated autophagy

HIGHLIGHTS

  • who: Xuyuan Wang from the (UNIVERSITY) have published the article: Influenza A virus use of BinCARD1 to facilitate the binding of viral NP to importin u03b17 is counteracted by TBK1-p62 axis-mediated autophagy, in the Journal: (JOURNAL) of 30/03/2022
  • what: The authors identified BinCARD1 as an important host factor in the replication of IAV.
  • how: Since BinCARD1 positively regulated the nuclear import of the vRNP complex and NP the authors investigated whether BinCARD1 binds to NP by performing co-IP experiments.

SUMMARY

    RNA quantification Total RNA . . .

     

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