Inherited determinants of early recurrent somatic mutations in prostate cancer

HIGHLIGHTS

  • who: Alessandro Romanel from the University of New York, NY, Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine, York Avenue, New York, NY, USA. have published the research work: Inherited determinants of early recurrent somatic mutations in prostate cancer, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors report a link between an inherited non-coding variant and prostate cancer somatic mutations through the interrogation of large cohorts of human data and experimental support of the functional activity of the variant locus. While the mechanism linking the 7p14.3 variant and SPOP . . .

     

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