HIGHLIGHTS
- who: Abbreviations Atg and collaborators from the (UNIVERSITY) have published the Article: Inhibiting Cytoprotective Autophagy in Cancer Therapy: An Update on Pharmacological Small-Molecule Compounds, in the Journal: (JOURNAL)
- what: The experiment shows that these MRT compounds inhibit autophagy by reducing the transformation of LC3-I to LC3-II. Much of the studies focused on repositioning the antimalarial drug chloroquine and its derivatives, which are indirect autophagy inhibitors that are inexpensive, safe, and readily available for clinical trials.
- future: In consideration of the functions of ULK1 in autophagy more work is needed to . . .
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