Inhibiting nlrp3 inflammasome activation prevents copper-induced neuropathology in a murine model of wilson’s disease

HIGHLIGHTS

• who: Jianjian Dong from the Participants were recruited from the Institute of Neurology, Affiliated Hospital, Anhui University of Chinese have published the Article: Inhibiting NLRP3 inflammasome activation prevents copper-induced neuropathology in a murine model of Wilson’s disease, in the Journal: (JOURNAL)
• what: The authors investigated how the activation of NLR family pyrin domain containing 3 (NLRP3) inflammasome contributes to copper-mediated neuroinflammation in an animal model of WD. The study demonstrates the contribution of copper overload-mediated activation of NLRP3 inflammasome to progressive neuropathology in the CNS of a murine model of WD . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.