HIGHLIGHTS
- who: Nicolas Dubuisson and collaborators from the National Ilan University, Taiwan have published the article: Inhibiting the inflammasome with MCC950 counteracts muscle pyroptosis and improves Duchenne muscular dystrophy, in the Journal: (JOURNAL)
- what: The aim of this work was to explore whether inflammasome blockade by MCC950 may play a beneficial role in DMD. The authors show by immunofluorescence the location and density of N-GSDMD in dystrophic muscle and the effect exe rted by MCC950.
SUMMARY
Ischemia or cholestatic liver injury. MCC950 was orally administered for a period of 2 months . . .
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