Inhibiting the unconventionals: importance of immune checkpoint receptors in t, mait, and nkt cells

HIGHLIGHTS

  • who: Elisa Catafal-Tardos and colleagues from the (UNIVERSITY) have published the research: Inhibiting the Unconventionals: Importance of Immune Checkpoint Receptors in T, MAIT, and NKT Cells, in the Journal: Cancers 2021, x of /2021/
  • what: The authors reason that it will be beneficial for CPI therapies to begin targeting non-MHC restricted anti-tumor T_cells, such as γδ T, NKT, or MAIT_cells.

SUMMARY

    Although the term "T lymphocyte" is synonymous with adaptive immune_responses generated by B and CD4+ or CD8+ alpha beta (αβ) T_cells, over the last 20 years or so, an . . .

     

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