Inhibition of abl kinase by imatinib can rescue the compromised barrier function of 22q11.2ds patient-ipsc-derived blood-brain barriers

HIGHLIGHTS

  • who: Yunfei Li and colleagues from the Department of Biomedical Engineering, The City College of the City University of New York, New York, NY, USA have published the research: Inhibition of Abl Kinase by Imatinib Can Rescue the Compromised Barrier Function of 22q11.2DS Patient-iPSC-Derived Blood-Brain Barriers, in the Journal: Cells 2023, 422 of 25/01/2023
  • what: The authors showed that imatinib, an inhibitor of Abl kinase, can rescue the The study provides much more detail on the molecular mechanism for understanding the anti-vascular leak effect of imatinib. For the . . .

     

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