Inhibition of autophagy promotes the elimination of liver cancer stem cells by cd133 aptamer-targeted delivery of doxorubicin

HIGHLIGHTS

  • who: Wang Yin and collaborators from the Deakin University, Geelong, VIC, Australia have published the research work: Inhibition of Autophagy Promotes the Elimination of Liver Cancer Stem Cells by CD133 Aptamer-Targeted Delivery of Doxorubicin, in the Journal: (JOURNAL)
  • what: In this study, the anti-hepatocellular carcinoma stem_cell effect of the combined treatment of CD133 aptamer-DOX and autophagy inhibitors was explored.

SUMMARY

    Accumulating evidence has shown that a small subset of liver cancer cells, termed liver tumor-initiating cells or liver cancer stem_cells, are responsible for the initiation, propagation, metastasis . . .

     

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