HIGHLIGHTS
- who: Tiziana Schioppa and colleagues from the Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy have published the research work: Inhibition of Class I Histone Deacetylase Activity Blocks the Induction of TNFAIP3 Both Directly and Indirectly via the Suppression of Endogenous TNF-, in the Journal: (JOURNAL)
- what: The authors characterized the effects of the HDI trichostatin A (TSA) on the expression of TNFAIP3 which is a crucial inhibitor of the classical NF-kB pathway and an LPS-induced negative feedback regulator. HDAC3 Knockdown Partially Recapitulated Inhibition by TSA Based on the observation . . .
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