Inhibition of erk1/2 or crmp2 disrupts alcohol memory reconsolidation and prevents relapse in rats

HIGHLIGHTS

  • What: The authors show here that the retrieval of alcohol-associated memories in rats with a history The authors demonstrate that the post-retrieval inhibition corticolimbic system. The authors show relapse is suppressed inhibition of CRMP2, addition, the authors show that relapse is suppressed post-retrieval inhibition of CRMP2,of a a translational product of mTORC1 signaling.byInthe contrast, the post-retrieval inhibition translational product of mTORC1 signaling. Of note, the Western blot analyses in this study were conducted on whole amygdala tissues, without further segregation into the amygdala sub-regions.
  • Who: Nofar Rahamim and . . .

     

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