Inhibition of il-12 heterodimers impairs tlr9-mediated prevention of early mouse plasmacytoma cell growth

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  • who: Mohamed F. Mandour from the University of Kent, United Kingdom have published the article: Inhibition of IL-12 heterodimers impairs TLR9-mediated prevention of early mouse plasmacytoma cell growth, in the Journal: (JOURNAL) of 13/01/2023
  • what: The aim of this work was to analyze in mouse experimental models by which mechanisms the interaction between infectious agent molecules and the early innate responses could enhance early inhibition of cancer growth and especially to assess the role of IL-12 by using novel antibodies specific for IL-12 heterodimers. Since CpG-ODN stimulation induced . . .

     

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