Inhibition of il-34 unveils tissue-selectivity and is sufficient to reduce microglial proliferation in a model of chronic neurodegeneration

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  • who: Diego Gomez-Nicola from the University of Freiburg, Germany have published the paper: Inhibition of IL-34 Unveils Tissue-Selectivity and Is Sufficient to Reduce Microglial Proliferation in a Model of Chronic Neurodegeneration, in the Journal: (JOURNAL)
  • what: Since IL-34 has been shown to be a tissue-restricted ligand of CSF1R, and it is crucial for the differentiation and maintenance of microglial cells in the brain, the authors aimed to investigate whether Frontiers in Immunology | www.frontiersin.org The authors explored the effect of inhibition of IL34 on blood monocytes, systemic tissue macrophages . . .

     

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