Inhibition of mir-4640-5p alleviates pulmonary hypertension in chronic obstructive pulmonary disease patients by regulating nitric oxide synthase 1

HIGHLIGHTS

  • who: Zhao Yang from the (UNIVERSITY) have published the paper: Inhibition of miR-4640-5p alleviates pulmonary hypertension in chronic obstructive pulmonary disease patients by regulating nitric oxide synthase 1, in the Journal: (JOURNAL)
  • what: The authors aimed to evaluate the expression and function of microRNA-4640-5p (miR4640-5p) in PH.
  • how: The results showed that the expression of miR-4640-5p was enhanced in PASMCs cultured under hypoxia with the highest levels at 72 h post hypoxia treatment (Fig 2A). The dual luciferase activity was analyzed in PASMCs at 48 h . . .

     

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