Inhibition of nedd8 neddylation induced apoptosis in acute myeloid leukemia cells via p53 signaling pathway

HIGHLIGHTS

  • who: Bioscience Reports ( and colleagues from the Department of Hematology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, PR. China have published the article: Inhibition of NEDD8 NEDDylation induced apoptosis in acute myeloid leukemia cells via p53 signaling pathway, in the Journal: (JOURNAL) of 16/08/2022
  • what: This study aimed to explore the activation of molecules associated with the NEDDylation pathway in AML and examine the effect of inhibiting NEDDylation on AML cells. This study demonstrated that the mRNA levels of NEDD8, UBA3, UBE2M and RBX1 were up-regulated in AML patients, consistent . . .

     

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