Inhibition of nedd8 neddylation induced apoptosis in acute myeloid leukemia cells via p53 signaling pathway

HIGHLIGHTS

• who: NEDD et al. from the Department of Hematology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, PRChina. have published the research work: Inhibition of NEDD8 NEDDylation induced apoptosis in acute myeloid leukemia cells via p53 signaling pathway, in the Journal: (JOURNAL)
• what: The authors observed that the mRNA expression levels of UBA3 UBE2M and RBX1 in patients were up-regulated compared with healthy controls which were correlated with worse overall survival (OS) of patients.
• future: In future studies the transfection conditions and methods will be activation of p53 transcription factor p21 . . .
  

   

  

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