Inhibition of neutrophil extracellular trap formation attenuates nlrp1-dependent neuronal pyroptosis via sting/ ire1 a pathway after traumatic brain injury in mice

HIGHLIGHTS

  • who: April and colleagues from the Paul-Ehrlich-Institut (PEI), Germany Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China, Key have published the Article: Inhibition of neutrophil extracellular trap formation attenuates NLRP1-dependent neuronal pyroptosis via STING/ IRE1 a pathway after traumatic brain injury in mice, in the Journal: (JOURNAL)
  • what: The authors hypothesized that NET formation promotes neuronal pyroptosis and neuronal cell death via STING/ IRE1a pathway after induction of TBI in mice.
  • how: The results showed that neuronal death was significantly reduced in the anti-Ly6G treatment group compared . . .

     

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