Inhibition of nlrp3 inflammasome activation by cell-permeable stapled peptides

HIGHLIGHTS

• who: Arumay Pal from the Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Biopolis Street, #07, Singapore School of Biological Sciences, Nanyang Technological University, Nanyang Drive, Singapore have published the paper: Inhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides, in the Journal: Scientific Reports Scientific Reports of 22/08/2018
• what: This work provides the first example of using peptide-based modulators to target components of the inflammasome pathway. The promising aspect will be addressed in future investigations aimed at understanding whether the ASC peptides designed in the study can . . .
  

   

  

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