Inhibition of plasmodium falciparum hsp70-hop partnership by 2-phenylthynesulfonamide

HIGHLIGHTS

  • who: . and colleagues from the McGill University, Canada have published the research: Inhibition of Plasmodium falciparum Hsp70-Hop partnership by 2-phenylthynesulfonamide, in the Journal: (JOURNAL)
  • what: The authors investigated the effect of PES on asexual blood-stage P. falciparum parasites and the authors established that it exhibits modest antiplasmodial activity. 3.1 PES is predicted to directly bind to both PfHsp70-1 and PfHop Molecular docking studies were conducted to assess the propensity of PES to bind to PfHsp70-1 and its co-chaperone, PfHop.
  • how: The following antibodies were used in . . .

     

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