Inhibition of the tlr/nf- κ b signaling pathway and improvement of autophagy mediates neuroprotective effects of plumbagin in parkinson ’ s disease

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  • who: Yan Su et al. from the Department of Physiology, Guilin Medical University, Guilin, Guangxi, China have published the paper: Inhibition of the TLR/NF- u03ba B Signaling Pathway and Improvement of Autophagy Mediates Neuroprotective Effects of Plumbagin in Parkinson u2019 s Disease, in the Journal: Oxidative Medicine and Cellular Longevity of 22/Dec/2022
  • what: The study demonstrated that plumbagin possesses antineuroinflammatory and autophagy-improving properties . The research showed that plumbagin inhibited inflammation via the TLR/NF-u03baB pathway, decreased TNF-u03b1, IL-1u03b2, and IL-6 mRNA expressions, and provided neuroprotection against subacute . . .

     

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