HIGHLIGHTS
- who: (https//creativecommons.org/licenses/by/ and collaborators from the Faculty of Chemistry, Warsaw University of Technology, ulNoakowskiego, Warsaw, Poland have published the paper: Inhibitors:, in the Journal: Pharmaceuticals 2022, 15, 949. of 28/07/2022
- what: The authors designed and synthesized a new library of small-molecule based on indol-4-yl-pyrazol pyrimidine with IC50 values in the low nanomolar range and high selectivity against the PI3Kδ isoform. According to mentioned in the above paragraphs' correlations, the authors focused on the pyrazol pyrimidine core as probably the most promising structure (including the nitrogen . . .
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