Inhibitory synapse dysfunction and epileptic susceptibility associated with kif2a deletion in cortical interneurons

HIGHLIGHTS

  • who: ufeffNuriaufeff ufeffRuiz-Reigufeff et al. from the Radboud, France have published the research: Inhibitory synapse dysfunction and epileptic susceptibility associated with KIF2A deletion in cortical interneurons, in the Journal: (JOURNAL)
  • what: The authors report that KIF2A is essential for tangential migration of cortical interneurons during development and for the formation and/or maintenance of inhibitory synapses in the adult brain. The authors assessed its function in tangential migration of cortical GABAergic interneurons.

SUMMARY

    Malformations of cortical development (MCD) are characterized by the interruption of one or more developmental processes in . . .

     

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