Initiation of hiv neutralizing b cell lineages with sequential envelope immunizations

HIGHLIGHTS

  • who: Wilton B. Williams from the Duke University have published the paper: Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors report here the immunogenicity in rhesus macaques and CH103 CD4-binding_site bnAb UCA KI mice of sequential Env immunogens derived from the CH505 HIV-1-infected individual who made the CH103 bnAb lineage. The authors report the number of antibodies isolated from each macaque per vaccine group studied, and the frequency of CH505 differential binders.
  • how: These results indicated that . . .

     

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