Initiation of pancreatic cancer: the interplay of hyperglycemia and macrophages promotes the acquisition of malignancy-associated properties in pancreatic ductal epithelial cells

HIGHLIGHTS

  • who: Lilli Otto and colleagues from the Institute for Experimental Cancer Research, Kiel University (CAU) and University Medical Center have published the research: Initiation of Pancreatic Cancer: The Interplay of Hyperglycemia and Macrophages Promotes the Acquisition of Malignancy-Associated Properties in Pancreatic Ductal Epithelial Cells, in the Journal: (JOURNAL) of 23/06/2017
  • what: This study aimed at gaining further insights into the mechanisms of how inflammatory conditions associated with metabolic disorders promote malignancy-associated alterations in PDEC. Expanding these findings, this study aimed at investigating whether concomitant exposure to macrophages and hyperglycemia further promotes . . .

     

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