HIGHLIGHTS
- who: Mariapia Vairetti et al. from the (UNIVERSITY) have published the research work: Innovative Molecular Target and Therapeutic Approaches in Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis (NAFLD/NASH) 2.0, in the Journal: (JOURNAL) of 14/07/2022
SUMMARY
Many pathophysiological mechanisms are involved in the development of NAFLD and its progression to NASH, such as: oxidative stress, lipotoxicity, intestinal microbiota dysbiosis, endocrine alterations, adipokine dysregulation, and endoplasmic_reticulum stress; lipotoxicity is discussed as a leading cause of NASH in the review by Branković et_al. The documented increased intestinal permeability results in hepatic macrophage . . .
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