Inosine monophosphate dehydrogenase type 2 polymorphism impdh2 3757t>c (rs11706052) and 12-month evolution of the graft function in renal transplant recipients on mycophenolate-based immunosuppression

HIGHLIGHTS

• What: The authors aimed to evaluate whether the rs11706052 variant allele had an effect on the evolution of the graft function over the first post-transplant year in patients whose maintenance immunosuppression included MPA. The authors intended to contribute to the following question: in renal transplant recipients in whom MPA is a part of maintenance immunosuppression, is the IMPDH2 3757T > C genotype a factor that should be taken into account (e_g, should the MPA dosing be adjusted)? Patients Eligible were adults (age ≥ 16 years) providing informed consent for genotyping and the use of anonymized data for research . . .
  

   

  

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