Inositol acylation of phosphatidylinositol mannosides: a rapid mass response to membrane fluidization in mycobacteria

HIGHLIGHTS

  • who: Peter P. Nguyen from the DepartmentUniversity of Amherst, MA, USA have published the article: Inositol acylation of phosphatidylinositol mannosides: a rapid mass response to membrane fluidization in mycobacteria, in the Journal: (JOURNAL)
  • what: Using chemical treatment and heat stress to fluidize the membrane, the authors show here that phosphatidylinositol (PI)-anchored plasma_membrane glycolipids known as PI mannosides (PIMs) are rapidly remodeled upon membrane fluidization in Mycobacterium smegmatis. The authors show that PIM inositol acylation is a rapid response independent of de novo protein synthesis, representing one of the fastest mass conversions of lipid molecules . . .

     

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