Inositol-requiring enzyme 1α/x-box protein 1 pathway expression is impaired in pediatric cholestatic liver disease explants

HIGHLIGHTS

• who: Alyssa Kriegermeier et al. from the Chicago, Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL have published the research work: Inositol-requiring enzyme 1u03b1/X-box protein 1 pathway expression is impaired in pediatric cholestatic liver disease explants, in the Journal: PLOS ONE of August/19,/2022
• what: The authors sought to evaluate the hepatic UPR expression in the livers of pediatric patients with severe cholestatic disease. This study was approved by the LCH institutional review board and written consent or a waiver of consent was obtained following LCH institutional review . . .
  

   

  

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