Insert-seq enables high-resolution mapping of genomically integrated dna using nanopore sequencing

HIGHLIGHTS

  • who: Dimitrije Ivanu010diu0107 from the Universitat Pompeu Fabra, Barcelona, Spain have published the research: INSERT-seq enables high-resolution mapping of genomically integrated DNA using Nanopore sequencing, in the Journal: (JOURNAL)
  • what: The authors develop INSERT-seq a that combines targeted amplification of integrated DNA UMI-based correction of PCR bias and Oxford long-read for robust analysis of DNA integrau2011 tion.
  • how: To study the effect of repetitive elements on capturing insertion sites the authors implemented a model that showed significant dependency of read length for accurately resolving insertion sites. Next the . . .

     

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