HIGHLIGHTS
- who: Yue Pan et al. from the University, UNITED STATES University School of Medicine, Heath Park, Cardiff, United Kingdom have published the article: Inside-out: Antibody-binding reveals potential folding hinge-points within the SARS-CoV-2 replication co-factor nsp9, in the Journal: PLOS ONE of April/10,/2023
- what: The authors demonstrate that VHH-binding, which occurs at a site distal to the NiRAN domain-interaction site, may nonetheless result in structural changes capable of disrupting a protein-interface.
SUMMARY
Nsp9 in_vitro VHH binding and produces subgenomic transcripts. The . . .
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