Insight into the interplay between mitochondria-regulated cell death and energetic metabolism in osteosarcoma

HIGHLIGHTS

  • who: Metformin et al. from the University of Padua, Italy have published the research: Insight into the interplay between mitochondria-regulated cell death and energetic metabolism in osteosarcoma, in the Journal: (JOURNAL)
  • what: In this review, the authors provide a thorough overview of the current knowledge on the mitochondria-related RCD machinery in OS, focusing on the molecular mechanisms of apoptotic and nonapoptotic RCD.
  • future: Studies are required to successfully target anti-apoptotic members to treat OS. Studies are needed to understand OS tumorigenesis and progression as well as for the development of . . .

     

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