HIGHLIGHTS
- who: Attila A. Seyhan and Claudio Carini from the Laboratory of Translational Oncology and Experimental Cancer Therapeutics, Warren Alpert Medical School, Brown University, Providence, RI, USA have published the article: Insights and Strategies of Melanoma Immunotherapy: Predictive Biomarkers of Response and Resistance and Strategies to Improve Response Rates, in the Journal: (JOURNAL)
- what: This study demonstrated that patients not responding to therapy have occasional genetic alterations in antigen presentation genes .
SUMMARY
The groundbreaking finding by Leach et_al showed that antibodies blocking the T_cell co-inhibitory receptor CTLA-4 can augment immune_responses . . .
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