Insights into processing and cyclization events associated with biosynthesis of the cyclic peptide kalata b1*

HIGHLIGHTS

• who: Brendon F. Conlan from the (UNIVERSITY) have published the Article: Insights into Processing and Cyclization Events Associated with Biosynthesis of the Cyclic Peptide Kalata B1*, in the Journal: (JOURNAL) of August/10,/2012
• what: The authors have expressed the Oak1 gene and mutants of this gene in N. benthamiana to determine which amino_acids within the processing sites of the Oak1 precursor protein are necessary for cyclization to occur.

SUMMARY

This circular structure bestows cyclotides with exceptional structural and proteolytic stability. Cyclotides appear to be cyclized by a protease-mediated biosynthetic . . .

 



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