Insulin activates hepatic wnt/β-catenin signaling through stearoyl-coa desaturase 1 and porcupine

HIGHLIGHTS

  • who: Ramp#x000E9 and gine Cabrae from the CNRS have published the research work: Insulin activates hepatic Wnt/β-catenin signaling through stearoyl-CoA desaturase 1 and Porcupine, in the Journal: Scientific Reports Scientific Reports of 13/Dec/2018
  • what: The aim of this study was to investigate the effect of insulin on the Wnt/β-catenin signaling pathway in liver and hepatocytes in culture, a topic poorly documented so far in this major insulin target organ. The authors showed that palmitoleate is sufficient to trigger Wnt signaling activity in primary cultured hepatocytes.
  • how: The . . .

     

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