HIGHLIGHTS
- who: Beatriz Merino from the Centro Investigaciu00f3n Biomu00e9dica en Red Diabetes y Enfermedades Metabu00f3licas Asociadas (CIBERDEM), Madrid, Spain University of California, Irvine (UCI MIND), Irvine, CA, USA have published the research: Insulin-degrading enzyme ablation in mouse pancreatic alpha cells triggers cell proliferation, hyperplasia and glucagon secretion dysregulation, in the Journal: (JOURNAL)
- what: The authors propose that loss of function in alpha cells contributes to hyperglucagonaemia in type diabetes. In this model it was shown that the response of beta cells to somatostatin is dependent on the cilia, consistent with the fact that the somatostatin . . .
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