Insulin-degrading enzyme, an under-estimated potential target to treat cancer?

HIGHLIGHTS

• who: Laetitia Lesire and collaborators from the (UNIVERSITY) have published the Article: Insulin-Degrading Enzyme, an Under-Estimated Potential Target to Treat Cancer?, in the Journal: Cells 2022, 11, 1228. of /2022/

SUMMARY

Its roles in diabetes_mellitus, insulin resistance, and Alzheimer`s disease have been explored for several years and suggest that IDE could be a potential target in these diseases. To the physiological and physiopathological roles of IDE in the diseases mentioned above, the authors review here the potential roles of IDE in cancer via both substrate hydrolysis activities and other functions . . .

 



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