Insulin-induced gene 1 (insig1) inhibits hiv-1 production by degrading gag via activity of the ubiquitin ligase trc8

HIGHLIGHTS

  • who: You Zhang from the You Zhang1, Jing Lu1, Jing Ma, and X Xinqi Liu, From the State Key Laboratory of Medicinal Chemical Biology, Department of Biochemistry and Molecular Biology, College of Life Sciences, Nankai University, Tianjin, China Edited by Qi-Qun Tang have published the article: Insulin-induced gene 1 (INSIG1) inhibits HIV-1 production by degrading Gag via activity of the ubiquitin ligase TRC8, in the Journal: (JOURNAL) of June/27,/2018
  • how: INSIG1 increases the degradation of HIV-1 Gag To determine in which step INSIG1 affects HIV-1 production the authors . . .

     

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