HIGHLIGHTS
- who: Jian-Zhi Zhao from the Department of Biochemistry Center, Hebei University, Shijiazhuang, China have published the research work: Integrated analysis of tRNA-derived small RNAs in proliferative human aortic smooth muscle cells, in the Journal: (JOURNAL)
- what: We reveal for the first time a significant difference in tsRNA expression profiles between proliferative and quiescent HASMCs.
SUMMARY
AS-tDR-000067 (tRFdb_ID: 3003a) targeted the promoter of p53 gene, and AS-tDR-000067 suppression inhibited HASMC proliferation by augmenting p53 levels. AS-tDR-000076 (tRFdb_ID: 3008a) targeted the 3′-UTR of MFN2 . . .
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