Integrated experimental-computational analysis of a heparg liver-islet microphysiological system for human-centric diabetes research

HIGHLIGHTS

• who: Belu00e9n Casas et al. from the Biomedical Engineering, University, TissUse GmbH, Berlin, Germany have published the research: Integrated experimental-computational analysis of a HepaRG liver-islet microphysiological system for human-centric diabetes research, in the Journal: (JOURNAL) of October/19,/2022
• what: The authors show that the computational model captures the complex dynamics of glucose-insulin regulation observed in the system and can provide mechanistic insight into disease progression features such as insulin resistance and u03b2-cell dynamics. The authors propose combining the HepaRG liver-islet MPS with a computational model to augment in_vitro . . .
  

   

  

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