Integrated genomic analyses of acral and mucosal melanomas nominate novel driver genes

HIGHLIGHTS

  • who: Meng Wang from the (UNIVERSITY) have published the paper: Integrated genomic analyses of acral and mucosal melanomas nominate novel driver genes, in the Journal: (JOURNAL) of April/14,/2021
  • what: Our meta-analyses of 147 acral and 93 mucosal melanomas identified PTPRJ, FER, SKP2, LZTR1, CIC, and PRKN as part of a long tail of driver events that deserves further study and characterization.
  • how: The authors used Fisher`s exact test to compare the frequency of pathogenic alterations between the two subtypes and examine the correlations among different types of alterations.
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