Integrated metabolomic and transcriptomic analyses of the synergistic effect of polymyxin-rifampicin combination against

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  • who: Mohd Hafidz Mahamad Maifiah from the Discovery Institute, Monash University, Melbourne, VIC, Australia have published the Article: Integrated metabolomic and transcriptomic analyses of the synergistic effect of polymyxin-rifampicin combination against, in the Journal: (JOURNAL)
  • what: In the present study, both metabolomic and transcriptomic data consistently showed that only the polymyxin B/rifampicin combination significantly perturbed the central carbon metabolic pathways including 5.23E-07 6.61E-06 glycolysis, TCA cycle and PPP in P. aeruginosa PAO1 (Fig 6).
  • how: The Principal Component Analysis (PCA) results showed that polymyxin B alone slightly . . .

     

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